Sterile animals and animals with known bacteria or without special pathogen need to be kept in sterile environment,this kind of environment is at present known as barrier environment in the world,that is,using a barrier to separate animals from surrounding pollution.
A. Isolation system
It is a system for breeding animals in a container with gloves and it is used to keep sterile animals and terrestrial animals. The cleanliness inside must be level 100 according to the requirements of microorganism, but rooms and operators shall not be considered as for sterile room.
B.Shield system
The sterile room with level 10,000-100,000 can be used as feeding room, which is mainly used for long-term breeding of animals without special pathogen. Strict management should be carried out when entering the room such as shower, change clothes,etc.
C.Semi-shield system
Broaden management of people and objects coming in and out of the room. The composition of the plane is roughly the same as the shield system.
D.Laminar frame system
Cages should be placed in a clean horizontal laminar air. It is commonly used in small scale breeding, but there is a risk of contamination in an ordinary room for feeding,operation and handling. Semi-shield can be supplemented.
E.Open system
It is the system for people, objects and air coming in and out of the room without eliminating pollution, but usually a certain degree of cleaning management should be carried out.
