Basic requirements for animal room design:
1.Site: quiet and hygienic
2. Layout: preparation area, feeding area and experimental area. People flow, goods flow and animal flow are separated (one-way); purification, sterilization, pest control are required.
3. Building: have a clean corridor, feeding room, pollution corridor and other rooms.
4. Air conditioning system: temperature, humidity and air velocity are controllable with certain amount of ventilation volume and air pressure.
5. Lighting: use fluorescent lamps for animal room without windows and use glass windows for animal room with windows to filter UV. 12h lighting and 12h dark are required.
6. Water supply: drinking water and purified water.
Configuration of animal room
Animal room, actively area and corresponding auxiliary room should be built according to different species and different levels of experimental animals. The site should be quiet and clean without adverse external influence.
Animal room must be full of light with good ventilation, have clean ground and no water accumulation; ceiling and walls must be easy to clean and disinfect; exterior walls, roof, ceiling, doors and windows and pinelines must be free from animals, mosquitoes and other pests. Indoor temperature should be controlled at in 18-29℃, relative humidity 40%-70%, noise 60dB.
The animal density in cages cannot be too large. Air supply device, exhaust device, cooling and heating equipment should be equipped. Dedicated sewage and drainage facilities must be built to prevent spread of pathogens. All cages should be cleaned and disinfected regularly. Pad material must be disinfected by hign temperature/pressure or drugs and replaced in time. Indoor ammonia concentrations must be below 15mg/m³.
