The seismic design of biosafety laboratories should comply with the relevant provisions of the current national standard "Code for Design of Building Foundations" GB50007. The anti-seismic fortification category of the three-level biosafety laboratory should be classified as special fortification, and the category of four-level biosafety laboratory should be classified as special fortification.
1. Cast-in-place reinforced concrete seismic wall structure
As the highest level of protection, most of the structures of Level 4 biosafety laboratories are cast-in-place reinforced concrete anti-seismic wall structures, and the enclosure structure walls are cast-in-place reinforced concrete walls; a few use cast-in-place reinforced concrete frame structures, and the enclosure structure walls are made of prefabricated concrete blocks; in addition, some laboratories use reinforced concrete and steel composite structures. The cast-in-place reinforced concrete anti-seismic wall structure is relatively widely used in level 4 biosafety laboratories, and it is also the structural form recommended by GB 50346-2011 "Technical Code for Building Biosafety Laboratories".
Generally, the first floor of the waste treatment floor is made into the basement, the first floor is the core laboratory, and the top floor is the air treatment room. The plane layout of laboratory buildings is relatively standardized, mostly regular rectangular planes with regular plane shapes. The difficult or controversial part in the design is the vertical irregularity of the structure. According to the functional layout of the laboratory:
The ground floor waste disposal room is a large and open room;
The laboratory part on the first floor is arranged with small bays and multiple partition walls, and the walls do not reach the top. Generally, it is a hard suspended ceiling at an elevation of 2.7m. If this floor is all experimental rooms, it will form a complete structural layer;
The air handling machine room on the top floor is a structure with large space and high floor height.
The height of the structure varies greatly along the vertical direction, and the first floor is arranged with multiple walls. Compared with the large space on the upper and lower floors, the lateral stiffness of the structure changes abruptly along the vertical direction. The force components are discontinuous, and the shape of the building is a particularly irregular building.
