1. The basic design idea of the laboratory
1.1 Focus of design
(1) Set according to the analysis method: physical and chemical analysis, instrument analysis, special project analysis, etc.;
(2) Set according to the nature of work: research and development, testing, pilot production, etc.;
(3) Set according to the purpose: cytological analysis, biological analysis, zoological analysis, physical and chemical analysis, etc.
1.2 Design layout
There are many styles of laboratory layouts, such as the one-line single-aisle laboratory layout, the square-shaped double-aisle laboratory layout, the large-room and small-room laboratory layout, and the mixed laboratory layout, which can be selected according to specific conditions.
It is recommended to consider the layout according to the actual workflow of the laboratory or the centralized setting of experimental rooms for the same purpose. Different experimental rooms (areas) can complete different experimental operations, and each experimental room (area) is arranged in the order of experimental operations. Specifically, it can be arranged according to the following workflow: sample flow, waste flow (poisonous waste flow).
1.3 Architecture and Public Works Design
The qualitative determination of the building, civil or production, is determined according to the specific use of the laboratory.
Architectural design considers the layout of the laboratory according to the relevant requirements in the "Code for Fire Protection Design of Buildings", and attention should be paid to the use of organic solvents in the laboratory. The consumption of organic solvents is closely related to the layout of the laboratory or the quality of the building. Design of relevant clauses in Fire Code.
If it is an old factory building renovation project, the structure needs to review the floor loads of heavy-loaded rooms such as large-scale sterilization cabinets and archives.
HVAC design is one of the key points of laboratory design, mainly including exhaust and air conditioning, and it is also one of the key contents of laboratory energy-saving design.
There are two ways to design the gas source: one is centralized supply in the park or factory area, and the pipeline is directly connected to the use point; the other is to supply gas from the gas cylinder, which is installed between the gas cylinders and sent to the gas use point through the confluence .
There are two ways to connect the public engineering pipelines in the experimental area: one is to route the lines in the floor or under the floor, and turn up to the point of use to directly connect to the point of use; the other is to lay pipes in the common interlayer, through the functional column or within a partition to the point of use.
Pay attention to the power supply design of high-power equipment (especially electric heating equipment) such as sterilization cabinets; consider regulated power supply and UPS for precision instruments; consider the separate grounding design of some precision instruments; consider reasonable network, monitoring and socket design, etc.
1.4 Fire protection and safety design
The laboratory layout needs to consider the fire evacuation corridor to meet the code requirements.
Set up the water fire-fighting system according to the requirements of the specification, and the pre-action sprinkler system can be considered for spraying, so as to avoid the loss of equipment caused by misspraying.
To control the total amount of reagents stored, choose reagent storage cabinets with ventilation.
If there is a hydrogenation reaction, it should be installed separately, with the area controlled to the minimum, arranged at the end of the building, designed according to the explosion-proof area, and taking into account sufficient pressure relief area and door bucket.
Personal protection safety measures such as emergency showers and eyewashers are set up in the experimental area.
Articles and personnel in contact with active bacteria should consider sterilization measures and do a good job in biological safety protection.
The layout of the quality inspection center of a pharmaceutical factory is mainly composed of the following functional rooms: ① Sample collection; ② Sample recording and distribution; ③ Sample analysis; ④ Reagent storage room; ⑤ Cleaning and drying room; ⑥ Culture medium preparation; meeting room; ⑨ file room; ⑩ staff office and restroom. Sample room, analysis auxiliary function room (including balance room, precision instrument room, standard product preparation room, etc.), public engineering auxiliary function room (including gas cylinder room, water making room, power distribution room, air conditioning machine room, etc.)
